For single seasons, From 1871 to 2009, (requiring IP≥40, SOp9≥9, BBp9≥7, HBP≥6 and At least 50% games in relief), sorted by greatest SO

  Cnt Player             **SO**   IP   SO/9  BB/9 HBP Year Age Tm  Lg  G   GS CG SHO GF  W  L  W-L% SV  H   R   ER  BB   ERA  ERA  HR  BF   AB  2B 3B IBB  SH  SF GDP  SB CS Pk BK WP   BA   OBP   SLG   OPS  OPS   Pit  Str
 ----+-----------------+-------+-----+-----+-----+---+----+---+---+--+---+---+--+---+--+--+--+-----+--+---+---+---+---+------+----+--+----+----+--+--+---+---+---+---+---+--+--+--+--+-----+-----+-----+-----+----+----+---- 
    1 Mitch Williams      129   108.2 10.68  7.79   7 1987  22 TEX AL  85   1  0   0 32  8  6  .571  6  63  47  39  94   3.23  140  9  469  361  7  2   7   4   3   8   6 11  8  2  4  .175  .353  .280  .633   71           
    2 Dennis Sarfate       86    79.2  9.72  7.00   7 2008  27 BAL AL  57   4  0   0 15  4  3  .571  0  62  47  42  62   4.74   95  8  359  285  7  2   2   2   3  11   6  2  1  1  6  .218  .367  .340  .707   87 1531  900 
    3 Ryne Duren           74    71.1  9.34  7.19   6 1962  33 LAA AL  42   3  0   0 16  2  9  .182  8  53  38  35  57   4.42   87  1  327  255  9  0   2   7   1   6  12  0  0  1  4  .208  .364  .255  .619   75           
    4 Carlos Marmol        71    59.1 10.77  8.34  11 2009  26 CHC NL  64   0  0   0 14  2  2  .500  5  33  25  24  55   3.64  121  1  272  201 11  1   3   4   1   5   2  0  1  1  5  .164  .369  .244  .613    0 1194  691 
    5 Ryne Duren           67    49   12.31  9.00   7 1960  31 NYY AL  42   1  0   0 17  3  4  .429  9  27  29  27  49   4.96   72  3  229  169  1  0   1   3   1   2   7  1  0  0  4  .160  .367  .219  .586   71           

Seasons/Careers found: 5.

 Photos from the George Grantham Bain Collection at the Library of Congress.